Fumaric acid ( Fumaric acid; Kyselina fumarova; Lichenic acid )

Catalog No. M17809 CAS No. 110-17-8

Fumaric acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling.

Purity : 98%

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Biological Information

Product Name

Fumaric acid
Note

Research use only, not for human use.
Brief Description

Fumaric acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling.
Description

Fumaric acid is a dicarboxylic acid. It is a oncometabolite or an endogenous, cancer causing metabolite. High levels of this organic acid can be found in tumors or biofluids surrounding tumors. Its oncogenic action appears to due to its ability to inhibit prolyl hydroxylase-containing enzymes.
Synonyms

Fumaric acid; Kyselina fumarova; Lichenic acid
Pathway

Endocrinology/Hormones
Target

THR
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

110-17-8
Formula Weight

116.1
Molecular Formula

C4H4O4
Purity

98%
Solubility

——
SMILES

C(=C/C(=O)O)\C(=O)O
Chemical Name

2-Butenedioic acid (2E)-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Chen X, et al. Fumaric acid production by Torulopsis glabrata: engineering the urea cycle and the purine nucleotide cycle. Biotechnol Bioeng. 2015 Jan;112(1):156-67.

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